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Information and References: Organicfacts.net | Wikipedia | NIH | MedicalMushroomInfo.com
Patient Resources and Related Organizations: Baseline of Health Foundation | EuroMed Foundation | Europepmc.org | Fungiforthepeople.org
News and Media: News-Medical.net | HealthNutNews.com
Clinical trials: Clinicaltrials.gov | WeHeal Guide to Researching Clinical Trials
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From Wikipedia – Although fungi products have been used in traditional and folk medicines, probably since pre-history, the ability to identify beneficial properties and then extract the active ingredient started with the discovery of penicillin by Alexander Fleming in 1928. Since that time, many additional antibiotics have been discovered and the potential for fungi to synthesize biologically active molecules useful in a wide range of clinical therapies has been extensively exploited.
Pharmacological research has now isolated antifungal, antiviral, and antiprotozoan, isolates from fungi.
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The fungus with probably the longest record of medicinal use, Ganoderma lucidum, is known in Chinese as líng zhī (“spirit plant”), and in Japanese as mannentake (“10,000-year mushroom”). In ancient Japan, Grifola frondosa was worth its weight in silver, although no significant therapeutic benefits have been demonstrated in humans.
Studies have shown another species of Ganoderma genus, Ganoderma applanatum, contains compounds with anti-tumor and anti-fibrotic properties.
Inonotus obliquus was used in Russia as early as the 16th century, and it featured in Alexandr Solzhenitsyn’s 1967 novel Cancer Ward.
Lichens have also been used in many folk medicine traditions to treat a wide range of ailments. Research has demonstrated a range of therapeutically significant compounds in a range of lichen species[4] but none are currently believed to be in use in mainstream medicine.
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